2026 Drug Metabolism and Disposition Imaging Intern (PhD)

Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie Interns.  

This internship involves developing new protocols and experimental workflows in the drug metabolism and disposition department of AbbVie. You will get the chance to: 

• Evaluate the impact of in-source decay and fragmentation on MALDI mass spectrometry imaging platforms.  
• Optimize and test novel instrumentation and workflows in mass spectrometry imaging. 
• Develop assays to enable localization of antibody drug conjugates in tissue.
• Implement iPRM-PASEF workflows to build a tissue ion atlas for zebra fish and/or any other organs of interest in toxicity studies.
• Combine MS imaging and LC-MS workflows to identify and quantify endogenous and therapeutic molecules of interest on the same or serial sections. 

Key responsibilities include: 

• Prepare samples for MS imaging including cryosectioning, matrix application by spraying or sublimation. 
• Acquiring MS data on Bruker timsTOF fleX, Agilent QqQ with MassTech AP/MALDI-UHR, and Waters DESI TQ-Absolute mass spectrometers.  
• Responsible for basic data acquisition, processing, and report writing. 
• Present results and key findings to supervisor, department, and at internal poster session.