Postdoctoral Associate - Valente Lab
ABOUT US:
Scripps Research is ranked the most influential institution in the world for its impact on innovation. We expand basic knowledge in the biosciences, and use these fundamental advancements to develop profound innovations that improve wellbeing. Our educational and training programs mold talented and committed students and postdocs into leading edge scientists. Scientists in the institute’s five academic research departments work hand-in-hand with researchers of the Scripps Research Translational Institute and Calibr to merge foundational studies in biology, chemistry and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine. Together, we cultivate new scientific leaders and expand the frontiers of knowledge to deliver medical breakthroughs to better human health around the globe. If you have a passion for making a difference, this could be your opportunity to join our transformative team.
POSITION TITLE: Postdoctoral Associate
POSITION SUMMARY:
The Valente laboratory in the Department of Immunology and Microbiology at the Scripps Research Institute in Jupiter - Florida https://www.scripps.edu/valente/ is seeking a highly talented, creative, independent self-motivated postdoctoral scholar. We focus on the characterization of molecular interactions occurring within a host cell that are critical for HIV transcription. Our goal is to develop therapeutics that block HIV-1, with special focus on those that help to reduce, eradicate, or suppress the reservoir of latently infected cells.
Ongoing projects include:
- Understanding of the full clinical potential of Tat inhibitors in in vivo models of HIV latency
- Mechanisms of Tat-independent HIV replication: implications on HIV reservoir formation
- Development of HIV latency promoting agents and their exploration for a functional cure
- Identification and characterization of chromatin regulators and host cellular factors regulating HIV latency and reactivation
REQUIREMENTS:
Ph.D. (or MD/PhD) in biological sciences such as virology, molecular biology, cell biology, biochemistry or immunology, with several international publications. Preference to candidates with experience with HIV.
This position will require:
- Expertise in virology such as cell culture, virus production, lentivirus vector production, p24 ELISA, flow cytometry, etc.
- Work in the BSL3 facility
- Expertise in biochemistry, IP, WB, protein expression and purification
- Epigenetics ChIP-Seq, ATAC-Seq, etc.
- Small molecule screening
- Work with primary cell models of HIV latency
- Excellent oral communication and written skills in English, with good organizational and analytical abilities.
Interested candidates should submit curriculum vitae, letter of interest, and the names and contact information of three individuals to provide letters of reference to Susana Valente: svalente@scripps.edu.
Compensation:
Commensurate with experience
The above statements describe the level of work performed and expected in general terms. The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice. Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment-at-will status of Scripps Research staff.
EEO Statement:
The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
COVID-19 update:
The safety and well-being of our candidates, our people and their families continues to be a top priority. Until restrictions change, interviews will be conducted virtually.