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Internship / Co-op Research Associate in Biology, Biochemistry, Cell Biology or BioInformatics

Internship / Co-op Research Associate in Biology, Biochemistry, Cell Biology or BioInformatics
Location: Boston, MA
Monte Rosa Therapeutics is seeking passionate Co-op Research Associates to help us to eliminate disease causing proteins through targeted protein degradation¬¬¬–a novel and exciting way of drugging proteins that until recently were considered un-druggable. The candidates will gain hands-on experience within a particular area of interest in an early-stage drug discovery environment. You will work with an industry leader who will direct and mentor you on your project, as well as expose you to other drug discovery projects and involve you in the process of solving complex biological questions. You will be joining a diverse, thoughtful, fun and collaborative environment that emphasizes teamwork and putting people first!

If you have an interest in any of the following areas, we will give you hands on educational experience within a high paced Drug discovery environment.

Bioinformatics / Computational Biology
• Mine public domain gene-expression signatures, improve custom Next-generation sequencing (NGS) data pipelines and develop analysis workflows leveraging cloud infrastructure
• Apply and refine state of the art computational methodology and integrative -omics analysis to uncover interesting patterns of drug activity, selectivity and mechanism of action
Structural Biology / Protein Sciences
• Assist in the characterization of ligand binding of biochemical/biophysical techniques.
• Discover and tease apart protein-protein binding interfaces with mutagenesis.
• Your contributions will provide insight into further structural biology studies.
Cell Biology 
• Determine if APC oncogenic mutations govern sensitivity of colorectal cancer cells to [target] degradation.
• Examine how perturbation [target] protein regulators can alter sensitivity to [target] degradation.
• Discover if phosphorylation of certain B-catenin amino acid residues are necessary or sufficient for sensitivity of [target] degradation.
 Qualifications:
• Our preference is for a student currently in a Master degree program in Biochemistry, Cell Biology, Bioinformatics or a life science. However, a motived Sophomore or Junior, currently enrolled in a BS program with an exceptional academic record would be considered.
• Strong desire to learn the most advance approaches to drug discovery
• Biology and Biochemistry centric individuals should have previous documented experience with mammalian cell culture, molecular biology / biochemical techniques (e.g. Elisas, Western Blot, PCR).
• Those interested in a more Bioinformatics focused experience, AWS, R, Python experience is preferred
• Enjoys working in a team-based environment


Interested Candidates may forward CV and Cover Letter letting us know your area of interest please forward to Careers-US@MonterosaTx.com

Monte Rosa Therapeutics rational approach in targeting disease-causing proteins for degradation will deliver pioneering therapies for cancer and other diseases. Delivering this new generation of treatments to the patients requires a conceptual change. Monte Rosa recognizes this urgent need and is missioned to develop innovative protein degraders as a solution. Combining deep knowledge, insight and leading-edge science, our integrated engine is built for that purpose.