Research Technician II - Center for Genomic Medicine

The Claussnitzer Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group. The Claussnitzer lab at MGH will build a large-scale biobank of adipose-derived mesenchymal stem cells and other specimens with the aim to perform population-scale natural genetic variation screens. This effort will seek to systematically link genetic variation to molecular and cellular phenotypes in the context of metabolic disease. We are looking for a talented Research Technician I/II who will contribute to build cell-based biobank and additional research efforts aimed at mapping genetic variations in metabolic cell types and understanding genetic regulation and cellular programs in health and metabolic diseases. This candidate will apply technologies combining the isolation of mesenchymal stem cells from different adipose depot, the isolation of hepatocytes and preparation of histology sections, execution of several molecular biology techniques to systematically link genetic risk variants to their effector genes and measure the impact on cellular metabolic functions using targeted assays and high-throughput and high-content profiling methodologies.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

• Prepares basic solutions and performs base-level procedures as assigned (i.e. – pipetting, cell and tissue culture, etc.)
• Maintains laboratory notebook
• Understands and applies basic scientific techniques
• Conducts analysis of results and may begin interpretation of results
• Sets up and prepares routine experiments as directed
• Prepares lab reagents, chemicals, instruments, and equipment
• May perform independent literature searches
• Assists with organizing materials for publication or presentation
• Maintains and orders supplies
• Attend and participate in lab and projected meetings, including preparing reports, slide decks and presenting progress

A Research Technician II performs the duties of a Research Technician I (above) and may also:

• Execute protocols of non-routine experiments
• Assist the PI(s) with determining the most suitable methodology
• Perform basic design and modification of protocols
• Calculate, transcribe, and analyze data
• Prepare and present reports
• Organize and summarize acquired data, using scientific and statistical techniques.
• Organize and/or draft material for the preparation of research papers, manuscripts, and other documents for publication and/or presentation.
• Participate in the design of experiments or field work.

SKILLS/ABILITIES/COMPETENCIES REQUIRED: 

• Ability to work independently and as a team member
• Good communication skills
• Computer literacy
• Working knowledge of clinical research protocols
• Ability to perform multiple tasks independently
• The Research Technician II should also possess:
• Analytical skills and the ability to resolve technical problems
• Ability to interpret acceptability of data results
• Working knowledge of data management programs
• Demonstrated competence in research techniques and methodologies

EDUCATION: 

Bachelor’s degree required.

EXPERIENCE:

• New graduates with some lab experience (via course work, internships, etc.) or those without any prior research experience will be considered for the Research Technician I position outlined above.
• Those with a minimum of 1 year of directly related work experience will be considered for a Research Technician II position.
• Experience with basic and advanced techniques in molecular biology, cell culture and/or biochemistry is highly advantageous. Basic computer skills and previous laboratory experience are required.