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Postdoctoral Research Fellow - Colorectal Cancer

Be a part of the legacy: Postdoctoral Research Fellow Program
Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

The Discovery Biologics department seeks a Postdoctoral Research Fellow to be a part of the vibrant scientific community focused on early discovery research at the Cambridge Research Labs. The research fellow will initiate and drive a project aimed towards the design and characterization of degrader-antibody conjugates (DACs) to treat colorectal cancer. The project will provide excellent opportunity to work in cutting edge, multidisciplinary, and highly collaborative research that will bring together researchers from the departments of Discovery Biologics, Chemistry, and Oncology. The work is expected to generate data on the potential of a novel class of highly specific and safe therapeutics to treat a cancer with high unmet needs.


  • Design DACs to target colorectal cancer cells
  • Generate and characterize DACs
  • Literature mining
  • Prepare and publish manuscripts with generated data
  • Attend and actively participate in department and group meetings
  • Attend and participate external conferences

Required/Preferred Skills:

  • Protein expression, purification, and characterization skills
  • Protein engineering skill is preferable
  • Experience with antibodies and antibody drug conjugates is preferable
  • Scientific curiosity and dedication
  • Good communication and interpersonal skills
  • Ability to work in highly matrixed environments

Minimum/Preferred Education Requirements:

  • PhD in Biophysics, Biochemistry, Protein Engineering, or related field OR will have completed a PhD within the next year
  • 0 – 2 years of postdoctoral experience


We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe. 
Who we are …
We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.
What we look for …
Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today.
In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.