Intern, ASO Purification Development

About Biogen: 

At Biogen, our mission is clear - we are pioneers in neuroscience. Biogen discovers, develops, and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Together, our employees create, commercialize, and manufacture transformative therapies for our patient population.   

We at Biogen are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients who we serve. We are focused on strengthening our foundation to advance our overall Diversity, Equity and Inclusion (DE&I) strategy and, most importantly, ensure all our employees feel included. 

As an intern or co-op at Biogen, you can expect to be placed on a real project, under the guidance of experienced professionals and subject matter experts who are invested in your career and academic growth. We also ensure that you have plenty of opportunities to build your network, learn more about our organization through weekly lunch and learns led by leaders from across the company, and join us for several fun events.  

Summary 

This application is for a 12-week internship role from June - August 2024. Resume review begins in January 2024. 

We are seeking a highly motivated and creative individual for a summer intern position that will provide an exciting opportunity to work in a collaborative Biopharmaceutical environment.  The candidate will gain hands-on lab experience in purification process development for antisense oligonucleotides (ASO).  

Position Description 

As an intern you will execute small scale chromatography experiments designed specifically to expand our understanding of Hydrophobic Interaction Chromatography fundamentals. The ideal candidate will have some lab experience handling either oligonucleotides or proteins and will learn column chromatography that is commonly used to purify ASOs.  In addition, you will learn rp-HPLC, UV-Vis, and mass spectrometry analytical techniques to support their studies. 

Key Responsibilities:  

Participate in oligonucleotide purification development discussions 

Operate AKTA Avant chromatography purification systems 

Assist in experimental design and troubleshooting  

Run in-house analytical testing including rp-HPLC, mass spectrometry, and product concentration analysis 

Organize, analyze, document, and present their experimental findings to the ASO department 

Qualifications: 

Some purification and/or analytical lab experience, preferably some independent work beyond lab classes  

Candidate should be able to work independently and be a team collaborator 

Good communication and documentation skills 

To participate in the Biogen Internship Program, students must meet the following eligibility criteria: 

Legal authorization to work in the U.S. 

At least 18 years of age prior to the scheduled start date 

Be currently enrolled in an accredited college or university 

Education

A BS or MS degree in chemical engineering, biochemistry, chemistry, or related field is required. 

Location 

Research Triangle Park, North Carolina, USA