Research Associate in Genetics of Cardiovascular Disease

Research Associate position to study the Genetics of Coronary Artery Disease

PI: Rajat Gupta, M.D.

Divisions of Genetics and Cardiovascular Medicine

Brigham and Women’s Hospital / Harvard Medical School

Boston, Massachusetts

Preferred start date: May-June, 2023.

SUMMARY

The Gupta Laboratory in the Divisions of Cardiovascular Medicine and Genetics is looking for a self-motivated, curious research assistant interested in using new genomic methods to study vascular disease. The successful candidate will work on projects to understand the cells that cause heart disease using single cell RNA-sequencing methods. We are looking for a team-oriented and hard-working candidate able to excel in a fast-track environment. They must be detail-oriented and exhibit strong problem-solving skills. Prior experience with molecular biology, RNA-sequencing, and/or cell biology is a plus but candidates at all levels of experience are encouraged to apply.

The Gupta lab at Harvard Medical School and Brigham and Women’s Hospital is dedicated to finding new mechanisms of vascular diseases such as coronary artery disease and stroke using genetics as a guide. We have successfully used genome-wide association studies, exome sequencing, single cell RNA-sequencing, ATAC-seq, and Perturb-seq methods to better understand the cellular processes that contribute to disease. Mentorship and guidance will be provided by the Principal Investigator (Dr. Gupta) and other members of the lab.

The successful candidate will be appointed to Harvard Medical School, Brigham and Women’s Hospital and the Broad Institute of Harvard and MIT. We collaborate will several labs at each institution, and the environment will provide the perfect environment to learn cutting edge skills and get experience working in a hospital/research institute.  

QUALIFICATIONS

• BS in a biology, genetics or related science field required.
• Experience with basic molecular biology techniques and prior cell culture experience.
• A passion for science and sense of urgency to find new medicines to benefit patients.

PRINCIPAL DUTIES AND RESPONSIBILITIES

1. Under general supervision, performs a variety of routine tests following established methodologies. Routine tests may include cell cultures, PCR, RNA extraction, and next-generation sequencing.
2. Prepares and maintains tissue cultures.
3. Record data, summarizes, and analyzes results using basic statistics.
4. Prepares laboratory reagents, chemicals, instruments, and equipment.
5. Maintains supplies inventory in accordance with departmental procedures.
6. Discusses progress of work regularly with supervisor.

If interested, please send a current CV to Raj Gupta at rgupta@bwh.harvard.edu. We are a fun and inclusive research group, aspiring to produce top science and scientists through attentive mentoring and access the incredible academic environment of Boston, Harvard Medical School, and the Broad Institute.