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Technical Assistant I - Weissman Lab

The Weissman lab at the Whitehead Institute/MIT/HHMI is seeking a motivated senior student interested in conducting research on the study of retinal and neuronal aging, as well as their rejuvenation. The research will involve the application of advanced functional genomic tools, single cell technologies, and animal physiology.  The lab is widely recognized for building innovative tools for broadly exploring organizational principles of biological systems. These include ribosome profiling, which globally monitors protein translation, CRISPRi/a for controlling the expression of human genes and rewiring the epigenome, and lineage tracing tools, to record the history of cells. More information can be found on the lab’s website:

About the Technical Assistant I role:
Under the guidance of senior postdoctoral associates, you will be helping to develop and implement new functional genomics tools for mammalian systems that will enable the team to tackle a wide range of biological questions. This position will involve working with multiple researchers to support their science – including assisting with cloning and cell culturing. This would be an ideal opportunity for a hardworking, passionate, self-motivated professional who enjoys managing multiple priorities and is looking for a 2-3 year career experience before beginning graduate school or medical school. 


What we provide:

  • A competitive compensation package with comprehensive health and welfare benefits
  • Exposure to cutting-edge research and working with a collegial, close-knit lab team
  • Opportunities to present data in group meetings
  • Opportunities for professional development including the potential to eventually take leadership on a project that supports the lab’s larger research goals based on your interests and capabilities
  • Weissman research technician ‘alumni’ have a great track record of being accepted to top-tier graduate and medical schools



Performs bench level experiments and small independent research projects to support scientific research objectives of the lab or group. Analyzes experimental data, addresses methodological problems in experimental protocols and results, and reports data to supervisor.   



  • Perform a variety of laboratory and investigative procedures – including routine experimental techniques such as culturing and maintaining mammalian cell culture lines, performing flow cytometry and cell sorting, cloning, standard basic molecular biology techniques, standard biochemical assays such as immunoblotting or affinity purification and basic fluorescence microscopy.
  • Work efficiently and cooperatively to assist Postdocs, Graduate Students, and other lab members with experiments.
  • Operate lab equipment and prepare and order necessary supply stocks.
  • Collect, verify, record and compile experimental data.
  • Participate in laboratory meetings and read literature applicable to the research area(s).
  • Operate and maintain laboratory equipment to complete investigations.
  • Prepare, order, and maintain stocks of necessary reagents, solutions and supplies.
  • General lab operations support to help maintain a safe, clean, and orderly lab environment.
  • Other tasks as required or assigned.



  • Bachelor’s degree in biological sciences is required
  • Prior experience working in a hands-on research lab is required
  • Understanding of basic molecular and cellular biology techniques (PCR, gel electrophoresis, etc.).
  • Prior mouse handling experience is a plus
  • Tissue culture of mammalian cells and molecular cloning skills is preferred
  • Excellent verbal and written communication skills.
  • Excellent organizational skills, time management skills, and attention to detail.
  • Proactive and self-motivated mindset with an eagerness to learn and grow.
  • Proficient computer skills with demonstrated proficiency in Microsoft Office Suite.
  • Knowledge of various scientific databases and publications preferred.

**Accepting applications through March 15, 2024.